MULTI-CLASSIFICATION OF EYE DISEASES USING A CNN-HARALICK HYBRID FRAMEWORK
DOI:
https://doi.org/10.25271/sjuoz.2025.13.4.1593Keywords:
Eye Diseases, CNN, Haralick, Hybrid Model, Spatial Analysis, Texture Analysis, Dual-Branch Architecture, Multi-ClassificationAbstract
The detection and classification of eye diseases, including Diabetic Retinopathy, Cataract, and Normal conditions, are critical in medical imaging for early diagnosis and treatment. This study proposes a hybrid CNN-Haralick model, leveraging the lightweight MobileNetV2 CNN architecture for spatial feature extraction and Haralick texture features extraction for texture analysis to enhance the accuracy of eye disease classification. A dual-branch architecture is employed, which fuses features from both the Convolutional Neural Network and the Haralick-based texture analysis at an early stage. The model is evaluated on a dataset consisting of images from multiple sources. Experimental results show that the hybrid CNN-Haralick model achieves an overall accuracy of 98% on the validation set, outperforming traditional CNN models. The model demonstrates exceptional performance, with a macro average F1-score of 98% for the three classes, and AUC-ROC scores of 100% for each category. The confusion matrix and classification report further validate the model's capability to accurately classify eye diseases, providing reliable decision support for clinicians. Additionally, the model's effectiveness is discussed in comparison with existing works, highlighting its superior performance in terms of both accuracy and computational efficiency.
Downloads
References
Al-Bander, B., Al-Nuaimy, W., Al-Taee, M., & Zheng, Y. (2017). Automated glaucoma diagnosis using deep learning approach. 2017 14th International Multi-Conference on Systems, Signals & Devices (SSD). https://doi.org/10.1109/SSD.2017.8166974
Bitto, A. K., & Mahmud, I. (2022). Multi categorical of common eye disease detect using convolutional neural network: a transfer learning approach. Bulletin of Electrical Engineering and Informatics, 11(4), 2378–2387. https://doi.org/10.11591/eei.v11i4.3834
Cleveland Clinic. (2022, November 14). Blindness (Vision Impairment): Types, Causes and Treatment. Cleveland Clinic. https://my.clevelandclinic.org/health/diseases/24446-blindness
Esteva, A., Robicquet, A., Ramsundar, B., Kuleshov, V., DePristo, M., Chou, K., Cui, C., Corrado, G., Thrun, S., & Dean, J. (2019). A Guide to Deep Learning in Healthcare. Nature Medicine, 25(1), 24–29. https://doi.org/10.1038/s41591-018-0316-z
Flaxman, S. R., Bourne, R. R. A., Resnikoff, S., Ackland, P., Braithwaite, T., Cicinelli, M. V., Das, A., Jonas, J. B., Keeffe, J., Kempen, J. H., Leasher, J., Limburg, H., Naidoo, K., Pesudovs, K., Silvester, A., Stevens, G. A., Tahhan, N., Wong, T. Y., Taylor, H. R., & Bourne, R. (2017). Global causes of blindness and distance vision impairment 1990–2020: a systematic review and meta-analysis. The Lancet Global Health, 5(12), e1221–e1234. https://doi.org/10.1016/s2214-109x(17)30393-5
Haralick, R. M., Shanmugam, K., & Dinstein, I. (1973a). Textural Features for Image Classification. IEEE Transactions on Systems, Man, and Cybernetics, SMC-3(6), 610–621. https://doi.org/10.1109/tsmc.1973.4309314
Haralick, R. M., Shanmugam, K., & Dinstein, I. (1973b). Textural Features for Image Classification. IEEE Transactions on Systems, Man, and Cybernetics, SMC-3(6), 610–621. https://doi.org/10.1109/tsmc.1973.4309314
Ibomoiye Domor Mienye, Swart, T. G., Obaido, G., Jordan, M., & Ilono, P. (2025). Deep Convolutional Neural Networks in Medical Image Analysis: A Review. Information, 16(3), 195. https://doi.org/10.3390/info16030195
Kiziltoprak, H., Tekin, K., Inanc, M., & Goker, Y. S. (2019). Cataract in diabetes mellitus. World Journal of Diabetes, 10(3), 140–153. https://doi.org/10.4239/wjd.v10.i3.140
Krizhevsky, A., Sutskever, I., & Hinton, G. E. (2012). ImageNet Classification with Deep Convolutional Neural Networks. Neural Information Processing Systems; Curran Associates, Inc.
Londhe, M. (n.d.). Classification of Eye Diseases using Hybrid CNN-RNN Models MSc Research Project Data Analytics. Retrieved October 21, 2022, from
Malik, S., Kanwal, N., Asghar, M. N., Sadiq, M. A. A., Karamat, I., & Fleury, M. (2019). Data Driven Approach for Eye Disease Classification with Machine Learning. Applied Sciences, 9(14), 2789. https://doi.org/10.3390/app9142789
Mateen, M., Wen, J., Hassan, M., Nasrullah, N., Sun, S., & Hayat, S. (2020, March 11). Automatic Detection of Diabetic Retinopathy: A Review on Datasets, Methods and Evaluation Metrics | IEEE Journals & Magazine | IEEE Xplore. Ieeexplore.ieee.org.
Ouda, O., AbdelMaksoud, E., Abd El-Aziz, A. A., & Elmogy, M. (2022). Multiple Ocular Disease Diagnosis Using Fundus Images Based on Multi-Label Deep Learning Classification. Electronics, 11(13), 1966. https://doi.org/10.3390/electronics11131966
Pooja Bidwai, Shilpa Gite, Pahuja, N., Kishore Pahuja, Kotecha, K., Jain, N., & Sheela Ramanna. (2024). Multimodal Image Fusion for the Detection of Diabetic Retinopathy Using Optimized Explainable AI-based Light GBM Classifier. Information Fusion, 111, 102526–102526. https://doi.org/10.1016/j.inffus.2024.102526
Pratap, U., Surico, P. L., Singh, R. B., Romano, F., Salati, C., Spadea, L., Musa, M., Gagliano, C., Mori, T., & Zeppieri, M. (2024). Artificial Intelligence (AI) for Early Diagnosis of Retinal Diseases. Medicina-Lithuania, 60(4), 527–527. https://doi.org/10.3390/medicina60040527
Sarki, R., Ahmed, K., Wang, H., & Zhang, Y. (2020). Automated detection of mild and multi-class diabetic eye diseases using deep learning. Health Information Science and Systems, 8(1). https://doi.org/10.1007/s13755-020-00125-5
Sarki, R., Ahmed, K., Wang, H., Zhang, Y., & Wang, K. (2021). VU Research Repository. VU Research Repository | Victoria University| Melbourne Australia.
Shukla, U. V., & Tripathy, K. (2023a). Diabetic Retinopathy. PubMed; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK560805/
Shukla, U. V., & Tripathy, K. (2023b). Diabetic Retinopathy. PubMed; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK560805/
Şükran Yaman Atcı, Güneş, A., Metin Zontul, & Arslan, Z. (2024). Identifying Diabetic Retinopathy in the Human Eye: A Hybrid Approach Based on a Computer-Aided Diagnosis System Combined with Deep Learning. Tomography, 10(2), 215–230. https://doi.org/10.3390/tomography10020017
Sushith, M., Sathiya, A., Kalaipoonguzhali, V., & Sathya, V. (2025). A hybrid deep learning framework for early detection of diabetic retinopathy using retinal fundus images. Scientific Reports, 15(1). https://doi.org/10.1038/s41598-025-99309-w
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Oluwaseyi Ezekiel Olorunshola, Nanji Emmanuella Lakan, Fatimah Adamu-Fika, Joshua Caleb Ishaya

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License [CC BY-NC-SA 4.0] that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work, with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online.