Histological Changes in Some Organs of The Female Rats Infected With Toxoplasma Gondii Parasite Isolated From Embryo of Aborted Sheep

  • Liqaa H. Al-Delami University of Mosul
  • Buthaina H. Al-Sabawi University of Mosul
  • Firas M. Basheer University of Mosul
  • Hafidh I. Al-Sadi University of Mosul
Keywords: Toxoplasma gondii, histopathological changes, Sheep

Abstract

The current study included identifying the lesions and the histological changes caused by the intracellular parasite Toxoplasma gondii, which was isolated from embryos of aborted ewes. Intraperitonially injected in 15 female albino rats (3 months old) with suspension containing 100 tissue cysts.Histological section showed after four months of injection a chronic infection characterized by autolysis in all sections, where the liver sections showed expansion in the central hepatic veins, congestion in sinusoidal curves with irregularity in hepatic cords, and the presence of parasites in the liver cells. The brain tissue showed vacuoles in the neurons with an increase in the number of Purkenji cells. Kidney sections were characterized by degenerative and necrotic changes in the endothelial cells of the proximal and distal convoluted tubules with Sloughing of necrotic and degenerated cells of the tubes which accumulated inside the cavity. The parasites appeared in the endothelial cells of the glomerular tufts. Ovary and the uterus showed increased vascular wall thickness, furthermore, the spleen showed autolytic changes, deposition of pigment with the presence of parasites within the cells.

Author Biographies

Liqaa H. Al-Delami, University of Mosul

Department of biology, Education College for Girls, University of Mosul, Iraq.

Buthaina H. Al-Sabawi, University of Mosul

Department of anatomy, College of medicine, University of Mosul, Iraq.

Firas M. Basheer, University of Mosul

Department of biology, Education College for Girls, University of Mosul, Iraq.

Hafidh I. Al-Sadi, University of Mosul

Department of pathology, College of Veterinary, University of Mosul, Iraq.

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Published
2014-12-30
How to Cite
Al-Delami, L., Al-Sabawi, B., Basheer, F., & Al-Sadi, H. (2014). Histological Changes in Some Organs of The Female Rats Infected With Toxoplasma Gondii Parasite Isolated From Embryo of Aborted Sheep. Science Journal of University of Zakho, 2(2), 276-284. Retrieved from https://sjuoz.uoz.edu.krd/index.php/sjuoz/article/view/223
Section
Science Journal of University of Zakho