THE SYNTHESIS, CHARACTERIZATION, DFT-OPTIMIZATION, BIOLOGICAL ASSAYS, AND HEAVY METAL STUDIES OF A NEW TETRA DENTATE DERIVATIVE LIGAND AND ITS COMPLEXES

Authors

  • Kwestan Namiq Aziz Department of Chemistry, Faculty of Science and Health, Koya University, Koya, KOY45, Iraq
  • Eman Ibrahim Alsalihi Department of Chemistry, Faculty of Science and Health, Koya University, Koya, KOY45,

DOI:

https://doi.org/10.25271/sjuoz.2025.13.3.1542

Keywords:

N3O Ligand, Butyric Acid, Schiff Bases, Wastewater Purification, Antimicrobial Studies, DFT-Optimizatione

Abstract

A new tetra dentate derivative ligand [(E)-N-((E)-(2-(((Z)-1-hydroxybutylidene) amino) phenyl) (isopropylimino) methyl) butyrohydrazonic acid] [N3O] type has been prepared from the condensation process of equimolar 2-aminobenzohydrazide, isopropyl amine and followed by another addition of butyric acid. Spectroscopic techniques as FT-IR, UV-visible, Mass spectrum, 1H,13C-NMR, T.L.C., Melting point, Conductivity measurements, Magnetic moment, DFT-optimization studies and other methods have been used to characterize the ligand and its new complexes with the general formula [L(M2)Cl3.H2O] (where M= NiII, CoII, CuII, MnII, CdII, and ZnII). Studying biological activity for the ligand and its complexes against two gram-positive and two gram-negative bacteria . The formed compounds were evaluated for antibacterial activity against two gram-positive and two gram-negative bacteria which are Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, and Pseudomonas aeruginosa. The developed ligand and its metal complexes performed well versus both kinds of bacteria Scheme 1

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Published

2025-07-04

How to Cite

Azeez, K. N. A., & Eman Ibraheem. (2025). THE SYNTHESIS, CHARACTERIZATION, DFT-OPTIMIZATION, BIOLOGICAL ASSAYS, AND HEAVY METAL STUDIES OF A NEW TETRA DENTATE DERIVATIVE LIGAND AND ITS COMPLEXES. Science Journal of University of Zakho, 13(3), 374–387. https://doi.org/10.25271/sjuoz.2025.13.3.1542

Issue

Vol. 13 No. 3 (2025): July-September issue

Section

Science Journal of University of Zakho

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Copyright (c) 2025 Kwestan Namiq Aziz , Eman Ibrahim Alsalihi

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